LINking microRNAs, kidney development, and Wilms tumors.

نویسندگان

  • Peter Hohenstein
  • Nicholas D Hastie
چکیده

In this issue of Genes & Development, Urbach and colleagues (pp. 971-982) provide compelling data suggesting a role for LIN28 in the pathogenesis of a significant percentage of Wilms tumors. These data extend our insights in the genetics underlying Wilms tumor development and emphasize the importance of stemness and microRNA-mediated processes in the origins of these tumors.

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عنوان ژورنال:
  • Genes & development

دوره 28 9  شماره 

صفحات  -

تاریخ انتشار 2014